Biological effects of noble gases.

The Possibility of Selective Adsorption and Sensing of the Noble Gaseous Species by the C20 Fullerene, the Graphene Sheets, and the N4B4 Cluster

There are only a handful reports about the sensor systems having the ability of detecting the existence of the noble gases. Chemical reluctance of these gaseous species causes them to have no chemical interactions like hydrogen bonding with the chemically designed nano-sized sensors. Noble gasses usually have no atomic charges nor do change the total polarity of the molecular sensor systems. Th...

Xenon preconditioning: molecular mechanisms and biological effects

Xenon is one of noble gases and has been recognized as an anesthetic for more than 50 years. Xenon possesses many of the characteristics of an ideal anesthetic, but it is not widely applied in clinical practice mainly because of its high cost. In recent years, numerous studies have demonstrated that xenon as an anesthetic can exert neuroprotective and cardioprotective effects in different model...

Noble Gases from the Planetary Nebula Stage of Stellar Evolution Implanted in Meteoritic

Exploring the Effects on Lipid Bilayer Induced by Noble Gases via Molecular Dynamics Simulations

Noble gases seem to have no significant effect on the anesthetic targets due to their simple, spherical shape. However, xenon has strong narcotic efficacy and can be used clinically, while other noble gases cannot. The mechanism remains unclear. Here, we performed molecular dynamics simulations on phospholipid bilayers with four kinds of noble gases to elucidate the difference of their effects ...

0353. Do the noble gases helium and argon exert neuroprotective effects in a rodent cardiac arrest model?

Introduction The noble gas xenon exerts neuroprotective effects after various insults, but availability of xenon is limited. Helium and argon are readily available noble gases, but the results of studies using helium as neuroprotective measure are mixed, and the effects of argon are less well studied. In a recent cardiac arrest (CA) study, 70% argon (in O2) administered for 1 hour post CA impro...

Selling candles in a post-Edison world: phasing with noble gases bound within engineered sites.

The utility of noble gases for phase determination has been limited by the lack of naturally occurring binding sites in proteins. Wild-type T4 lysozyme contains one such binding site. By mutating large hydrophobic residues to alanine, additional noble-gas binding sites have been successfully introduced into this protein. Using data from xenon derivatives of the wild type, two single mutants and...